Elution Test of an Ionic 68Ga Generators
نویسندگان
چکیده
The 68Ga generator, obtained from New England Nuclear, Boston MA, USA through the Japan Radioisotope Association, uses 68Ge fixed by tin dioxide (SnO2) and placed in a glass column. This column is connected to inlet and outlet tubes and placed in a small lead casing. The generator activity was measured by an ionization chamber from the top (the top shield was removed for measurements). The eluate activities were also measured with an ionization chamber or a Ge(Li) semiconductor detector. Germanium-68 breakthrough is determined by a scintillation counter from the daughter 68Ga present in the eluate at least 72 hours after the end of elution. Standard analytic reagent grade The activity of the generator in three elution at 68 minute intervals. About 62% of the radioactivity of the generator was removed by the first elution. The rest (38%) was unchanged by the consecutive elutions. Fig. 1 Elutions and generator activity.
منابع مشابه
Methods of increasing the performance of radionuclide generators used in nuclear medicine: daughter nuclide build-up optimisation, elution-purification-concentration integration, and effective control of radionuclidic purity.
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